Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease (NCT06688968) | Clinical Trial Compass
RecruitingNot Applicable
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
France120 participantsStarted 2025-02-04
Plain-language summary
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects.
The main questions it aims to answer are:
1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects.
2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up.
Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including :
* A semi-structured interview to check the participants eligibility and gather demographic data.
* Neuropsychological tests and questionnaires will then be administered.
* A relative of the study participant will help complete questionnaires.
Who can participate
Age range
60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
General inclusion criteria:
* 60 years and older
* French-speaking and volunteering for the study
* Living at home with a relative
Alzheimer's disease inclusion criteria:
* Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)
* MMSE greater than or equal to 20
Inclusion criteria Parkinson's disease :
* Diagnosis of Idiopathic Parkinson's disease
* MMSE greater than or equal to 20
Exclusion Criteria:
* No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)
* Autistic disorders
* History of stroke or head trauma
* Unstable medical condition (cancer)
* Subject unable to read and/or write
* Hearing impairment without hearing aids
* Refusal of consent after information
* Persons unable to give consent, research carried out in emergency situations, etc.)
* Non-affiliation with a social security scheme
* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)
* Person under legal protection (guardianship, curatorship, legal protection)
* Person participating in another research project with an exclusion period still in progress
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Comparison of the specificities of musical engagement (i.e., music-related behaviors in daily life) in Alzheimer's disease, Parkinson's disease, and among a population of healthy old adults.