CompletedPhase 4

Effects of Intrauterine Flushing With Human Chorionic Gonadotropin on ICSI Outcome

Iraq90 participantsStarted 2022-10-23

Plain-language summary

a number of infertile women who were prepared for ICSI and immediately post ova pick up intrauterine flushing with human chorionic gonadotropin was done to study the effect of this drug on ICSI outcome and ultrasound parameter.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. The patient\'s consent to participate in the research study is crucial for data collection and analysis.
✓. Each pair of individuals undergoing IVF/ICSI procedures typically possess grade 1 (G1) embryos during the embryo transfer process.
✓. The age range of the female participants varied from 18 to 40 years.
✓. Infertility arising from female factors, including issues like blocked fallopian tubes, lack of ovulation, and unexplained fertility challenges, was examined.
✓. Male-related factors contributing to infertility were also taken into consideration.
✓. The procedure involved the transfer of grade one embryos during a fresh cycle.

What they're measuring

Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer

Timeframe: at day of ova pickup a blood sample aspirated, and on day of embryo transfer about 3-5 days post ova pickup blood sample taken within ten minute before embryo transfer to asses serum level of TNF-alfa and IL-10 for all participent

Ultrasound Parameter (RI,PI)

Timeframe: Within 10 minutes after ova pickup, ten minute before embryo transfer using ultrasound device

Systole Flow/ Diastole Flow

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

TNF-alfa/IL-10 Ratio

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

Trial details

NCT IDNCT06684951

SponsorOmayma Ismail Khalaf

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-23

Results submitted2024-11-25

View on ClinicalTrials.gov More Female Infertility trials

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. The patient\'s consent to participate in the research study is crucial for data collection and analysis.
✓. Each pair of individuals undergoing IVF/ICSI procedures typically possess grade 1 (G1) embryos during the embryo transfer process.
✓. The age range of the female participants varied from 18 to 40 years.
✓. Infertility arising from female factors, including issues like blocked fallopian tubes, lack of ovulation, and unexplained fertility challenges, was examined.
✓. Male-related factors contributing to infertility were also taken into consideration.
✓. The procedure involved the transfer of grade one embryos during a fresh cycle.

What they're measuring

Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer

Ultrasound Parameter (RI,PI)

Timeframe: Within 10 minutes after ova pickup, ten minute before embryo transfer using ultrasound device

Systole Flow/ Diastole Flow

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

TNF-alfa/IL-10 Ratio

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup