CompletedPhase 4

Effects of Intrauterine Flushing With Human Chorionic Gonadotropin on ICSI Outcome

Iraq90 participantsStarted 2022-10-23

Plain-language summary

a number of infertile women who were prepared for ICSI and immediately post ova pick up intrauterine flushing with human chorionic gonadotropin was done to study the effect of this drug on ICSI outcome and ultrasound parameter.

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. The patient\'s consent to participate in the research study is crucial for data collection and analysis.
. Each pair of individuals undergoing IVF/ICSI procedures typically possess grade 1 (G1) embryos during the embryo transfer process.
. The age range of the female participants varied from 18 to 40 years.
. Infertility arising from female factors, including issues like blocked fallopian tubes, lack of ovulation, and unexplained fertility challenges, was examined.
. Male-related factors contributing to infertility were also taken into consideration.
. The procedure involved the transfer of grade one embryos during a fresh cycle.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer

Timeframe: at day of ova pickup a blood sample aspirated, and on day of embryo transfer about 3-5 days post ova pickup blood sample taken within ten minute before embryo transfer to asses serum level of TNF-alfa and IL-10 for all participent

Ultrasound Parameter (RI,PI)

Timeframe: Within 10 minutes after ova pickup, ten minute before embryo transfer using ultrasound device

Systole Flow/ Diastole Flow

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

TNF-alfa/IL-10 Ratio

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

Trial details

NCT IDNCT06684951

SponsorOmayma Ismail Khalaf

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-23

Results submitted2024-11-25

View on ClinicalTrials.gov More Female Infertility trials

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. The patient\'s consent to participate in the research study is crucial for data collection and analysis.
. Each pair of individuals undergoing IVF/ICSI procedures typically possess grade 1 (G1) embryos during the embryo transfer process.
. The age range of the female participants varied from 18 to 40 years.
. Infertility arising from female factors, including issues like blocked fallopian tubes, lack of ovulation, and unexplained fertility challenges, was examined.
. Male-related factors contributing to infertility were also taken into consideration.
. The procedure involved the transfer of grade one embryos during a fresh cycle.

What they're measuring

Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer

Ultrasound Parameter (RI,PI)

Timeframe: Within 10 minutes after ova pickup, ten minute before embryo transfer using ultrasound device

Systole Flow/ Diastole Flow

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup

TNF-alfa/IL-10 Ratio

Timeframe: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup