Attention Bias Modification for the Improvement of Anxiety in Adolescent and Young Adult Cancer S… (NCT06682039) | Clinical Trial Compass
CompletedNot Applicable
Attention Bias Modification for the Improvement of Anxiety in Adolescent and Young Adult Cancer Survivors
United States70 participantsStarted 2024-11-08
Plain-language summary
This clinical trial studies how well attention bias modification (ABM) improves anxiety in adolescent and young adult (AYA) cancer survivors. Cancer-related anxiety is the most prevalent mental health problem affecting AYA cancer survivors. Cancer-related anxiety is associated with long-term negative outcomes such as poor quality of life, depression, distress, substance use, sleep problems, fatigue, and pain. ABM uses techniques to help patients change the way they react to environmental triggers that may cause a negative reaction. ABM uses brief self-guided smartphone applications. Patients complete repetitive association reaction-time tasks targeting automatic and unconscious negative attention biases to retrain attention away from perceived threat and towards a neutral or positive stimuli. Gratitude-finding and savoring activities are also provided to maintain and increase positive emotions. Using ABM plus gratitude-finding and savoring activities may improve anxiety in AYA cancer survivors.
Who can participate
Age range
15 Years – 29 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 15-29 years
* Diagnosis of cancer malignancy
* Received active/curative cancer treatment OR received/actively receiving cancer survivorship care at Seattle Children's Hospital (SCH) or other study referring site (e.g. St. Jude)
* Currently off active/curative cancer treatment
* Patient able to understand/read/write English language
* Cognitively able to participate in ABM intervention and complete surveys
* Patient has access to smartphone able to send and receive text messages
* Patient has access to computer or smartphone for Inquisit program
Exclusion Criteria:
* Patients on active/curative cancer treatment
* Cognitively or physically unable to participate in ABM intervention and surveys
* Patients who cannot understand/read/write English will be excluded from the research because the ABM intervention is currently only available in English
* Furthermore, patients who do not have access to technology (smartphone/computer) will be excluded from the study as this technology is absolutely required to engage in the study intervention
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Clinic recruitment rates
Timeframe: Up to 4 weeks post-intervention
2
Retention rates
Timeframe: Up to 4 weeks post-intervention
3
Patient acceptability of ABM: Client Satisfaction Questionnaire (CSQ-8)
Timeframe: At 4 weeks post intervention
4
Patient acceptability of ABM: System Usability Scale (SUS)