Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic S… (NCT06681207) | Clinical Trial Compass
RecruitingNot Applicable
Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke
United States108 participantsStarted 2025-04-23
Plain-language summary
This research study aims to understand the relationship between brain stimulation and leg skill learning in both healthy adults and persons with chronic stroke.
Who can participate
Age range
21 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age between 21 and 90 years
. Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
. MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
. Hemiparesis involving the lower extremity (Fulg-Meyer LE motor test)
. No passive range of motion limitation in bilateral hips and knees
. Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less
. Visual acuity can be corrected by glasses or contact lens to 20/20
. Able to walk independently with/without assistant devices for 10 meters
Exclusion criteria
. Pregnant women
. MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or malignant neoplasm or tumors
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Mean change from baseline in stepping motor control after five sessions of brain stimulation combined with visuomotor stepping learning
Timeframe: Day 1, Day 5, Day 7, Day 30, Day 60, Day 9 post five sessions of brain stimulation combined with visuomotor stepping training
2
Mean change from baseline in brain neuronal activations after five sessions of brain stimulation combined with visuomotor stepping learning
Timeframe: Day 1, Day 5, Day 7, Day 30, Day 60, Day 9 post five sessions of brain stimulation combined with visuomotor stepping training
Trial details
NCT IDNCT06681207
SponsorThe University of Texas Medical Branch, Galveston