Not Yet RecruitingNot Applicable

Early Ascitis Parencentesis in SBP

France50 participantsStarted 2024-11-11

Plain-language summary

Paracentesis at 48 hours, as recommended in international guidelines, could delay the time to effective antibiotic therapy in cases of SBP with germs resistant to empirical antibiotic therapy. Earlier paracentesis at 24 hours could save time in initiating the right antibiotic therapy and improve prognosis.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men and women aged 18 or over * Affiliation with a French social security * Signature of the informed consent form * Cirrhosis * Ascites fluid infection with PNN \> 250/mm3 Exclusion Criteria: * Pregnant women * Persons deprived of their liberty by judicial or administrative decision; persons under psychiatric care. * Adults under legal protection * Subjects within the exclusion period of another study * Other cause of abdominal infection than SBP * Intra-abdominal surgery \< 4 weeks

What they're measuring

Evaluate the percentage drop in neutrophils in ascites on Day 1

Timeframe: 24 hours

Trial details

NCT IDNCT06679842

SponsorCentre Hospitalier Universitaire de Besancon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-31

Contact for this trial

Jean Paul CERVONI, Hospital Practioner

+33 3 81 66 80 20 jpcervoni@chu-besancon.fr

View on ClinicalTrials.gov More Cirrhosis trials