Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption. (NCT06678386) | Clinical Trial Compass
By InvitationNot Applicable
Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.
Thailand58 participantsStarted 2024-10-01
Plain-language summary
The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences. The main questions it aims to answer are:
* Does sweet intensity change after reducing daily sugar intake by 50% for 12 weeks?
* How does sweet intensity change after completing dietary modification for 8 weeks?
* Does individual daily sugar intake change after completing dietary modification for 8 weeks?
Researchers will compare reducing daily sugar intake by 50% for 12 weeks to an unmodified diet to see if sugar reduction can change sweet intensity.
Participants will:
* Reduce daily sugar intake by 50% or maintain an unmodified diet for 12 weeks.
* Visit the clinic three times for anthropometric measurements, sweet perception tests, and to complete questionnaires.
* Keep a diet record for a total of 15 days during the research period.
Who can participate
Age range
18 Years – 59 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* People with a fasting blood sugar level below 126 mg/dL or an HbA1C below 6.5% in the past 6 months, who are not currently being treated for diabetes.
* People who score 10 or more points on the sweet food consumption behavior questionnaire.
* People who are able to communicate in the Thai language.
* People who are able to chat and use video calls via the Line application.
* People who agree to modify their diet and beverages according to the recommendations of a dietitian.
* People who agree to undergo sweet taste testing, complete a food record, and fill out a questionnaire.
Exclusion Criteria:
* People with uncontrolled chronic conditions who have had changes in their treatment within the past 3 months.
* People with a history of severe illness in the past 6 months.
* People who regularly use medication, excluding contraceptives and vitamins.
* Pregnant women.
* People who have experienced a weight change of at least 10% over the past 3 months.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Sweet intensity change from baseline after 12 weeks of the intervention.
Timeframe: 16 weeks from baseline (12 weeks after the start of the intervention)