Effectiveness of Early Intervention in Transfusion Independent Aplastic Anemia: a Retrospective Medical Claims Database Study

Inclusion Criteria: * Having at least one confirmed diagnosis of AA within the selection period (1 inpatient or 2 outpatient claims per the International Statistical Classification of Diseases, 10th Revision \[ICD-10\] code, without any suspicion flag). * Being aged 15 to 90 years at the index date. * Having at least 3 months of continuous enrolment prior to the index date. Exclusion Criteria: * Having a blood transfusion recorded any time before the index date. * Having anti-thymocyte globulin (ATG) treatment recorded within 3 months after the index date. * Having at least one prescription record for any of the drug treatments of interest any time before the index date. * Having a diagnosis of acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML) or other leukemia any time before the index date. * Having an AA diagnosis (without suspicious flag) date earlier than the start of patient's observation in the database. * Having less than 6 months of continuous follow-up. Safety Population - Additional Exclusion Criterion: \- Having a diagnosis of hepatotoxicity, kidney dysfunction, hypertension, or diabetes mellitus any time before the index date.