Stopped: Enrollment is currently paused. Aim 1 recruitment has finished, and the study team is preparing to begin Aim 2 recruitment.
This clinical trial compares the effect of the Helping Ovarian Cancer Patients Cope with Their Disease (HOPE) intervention to usual care for the reduction of hopelessness and helplessness in patients with ovarian cancer that has come back after a period of improvement (recurrent). Patients with recurrent ovarian cancer are at high risk for increased death and poor mental health outcomes, including depression and anxiety. Ovarian cancer is the deadliest of all gynecologic cancers, with a survival rate at five years of only 50%. Most patients are diagnosed with advanced disease and have a high chance of recurrent disease that is incurable, even if upfront treatments are effective. Ovarian cancer's advanced diagnosis, high likelihood of recurrence and death, and rigorous treatment including surgery and other cancer therapies create high levels of distress and reduced quality of life (QOL). Patients with recurrent ovarian cancer report high rates of depression and anxiety and poor QOL. Due to the major distress, reduced QOL, and likelihood of death among this population, improving this patient population's QOL is a priority. Using the HOPE intervention may be effective in reducing hopelessness and helplessness in recurrent ovarian cancer patients.
Age range
18 Years
Sex
FEMALE
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Accrual rates (Aim 1)
Timeframe: At the time of enrollment
Fidelity rates (Aim 1)
Timeframe: Up to 28 days
Rates of intervention completion (Aim 1)
Timeframe: Up to 28 days
Acceptability of the HOPE intervention (Aim 1)
Timeframe: Up to 28 days
Overall satisfaction (Aim 1)
Timeframe: Up to 28 days
Change in hopelessness/helplessness (Aim 2)
Timeframe: Baseline to 12 weeks post-randomization