By InvitationNot Applicable

Pilot Study to Characterize the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of CLn® Skin Care Body Wash

United States15 participantsStarted 2025-01-14

Plain-language summary

In this pilot study of patients with mycosis fungoides, the most common form of CTCL, we propose to primarily evaluate the impact of daily use of the CLn Body Wash (dilute sodium hypochlorite (0.006% NaOCl)) on the microbiota of CTCL lesions. Should dilute sodium hypochlorite body wash improve the microbiome of MF, reducing the abundance of S. aureus, future, larger studies can more fully evaluate the impact on pruritus, erythema, scaling, disease evolution and its role in CTCL management.

Who can participate

Age range18 Years – 89 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults ages 18-89 years of age with active mycosis fungoides. * Patients with concurrent and prior malignancies are allowed as long as any concurrent malignancy does not directly involve the same skin site. Exclusion Criteria: * Patients currently or recently (within past 4 weeks) on topical or systemic antibiotics, pregnant persons, or persons with potential of becoming pregnant or are/will be breastfeeding * Patients that have initiated a new skin-directed therapy over the past month.

What they're measuring

Change of S. aureus skin microbiome

Timeframe: 8 weeks

Trial details

NCT IDNCT06665490

SponsorNorthwestern University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-06

View on ClinicalTrials.gov More Cutaneous T Cell Lymphoma trials