Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders

Inclusion Criteria: * All participants: * 18 years of age or older * The participant must be able to comprehend and sign an approved Informed Consent Form and other applicable study documents. * Healthy volunteers: * No significant sinonasal/pulmonary symptoms or prior diagnoses of sinonasal/pulmonary conditions as determined by pre-enrolment questionnaires. * Case goup: * Participants must be previously diagnosed with rhinitis, chronic sinusitis, asthma, or COPD by a medical professional. Exclusion Criteria: * Less than 18 years of age at the time of enrolment. * Volunteers who are actively pregnant * Prior history of adverse reaction or contraindicated to diagnostic testing including fingerprick blood sampling, pulmonary testing, nasal swab/sampling. * Any other conditions limiting the volunteer's ability to complete study requirements in the judgement of the investigator/clinician * Any nasal anatomical issue or finding which may limit the safe insertion of the ABEL collection device, as determined by investigator/clinician * History of nasal surgery or trauma within the last 3 months