Quantitative Flow Ratio (QFR) has shown good diagnostic performance against Fractional Flow Reserve (FFR) in several meta-analyses, comparable or even superior to nonhyperemic pressure ratios. However, the reproducibility of QFR is modest and there is high inter- and intra-observer variability even when fairly experienced but non-core lab operators (at least 150 QFR procedure experience) are performing the analysis. Although smaller studies have demonstrated that non-core analysis and even paramedical user analysis can have good correlation with FFR, the concern about the diagnostic performance of QFR in real-world clinical practice by inexperienced users remains. The primary objective of "Dedinje FFR/QFR Registry" is to determine the feasibility and diagnostic performance of QFR analysis by vendor-certified inexperienced medical users in a real-world setting using FFR as the gold standard. All patients \>18 years old who present to the Institute for Cardiovascular Diseases "Dedinje" and undergo a planned or ad hoc FFR procedure will be asked to participate in the registry. FFR procedure is performed according to the standardized institutional protocol. QFR analysis will be subsequently performed offline according to a standard operating procedure.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Correlation between Quantitative Flow Ratio (QFR) and Fractional Flow Reserve (FFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Sensitivity of Quantitative Flow Ratio (QFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Specificity of Quantitative Flow Ratio (QFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Positive predictive value of Quantitative Flow Ratio (QFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Negative predictive value of Quantitative Flow Ratio (QFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Diagnostic gray zone
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)
Diagnostic accuracy of Quantitative Flow Ratio (QFR) against Fractional Flow Reserve (FFR)
Timeframe: at the time of Quantitative Flow Ratio (QFR) analysis completion (up to 1 year)