CompletedNot Applicable

Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses

Switzerland46 participantsStarted 2024-10-25

Plain-language summary

Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation. This study aims to investigate the extent and duration of the acute iron-induced effect on serum ferritin, as well as its protein characteristics, following the administration of a single iron dose

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Low iron stores (SF levels \< 30 µg/L), * no anemia (Hb \> 120 g/L) * no inflammation (CRP \< 5 mg/L) * 18 to 45 years old. * Body weight \<70 kg * Normal body Mass Index (18.5-26.5 kg/m2) Exclusion Criteria: * Any chronic or acute disease * Consumption of mineral and vitamin supplements since screening and over the study period * Blood transfusion, blood donation or significant blood loss over the past 6 months, * Pregnant or breastfeeding, * Continuous/long-term use of medication during the whole studies (except for contraceptives) * Therapeutic iron infusion over the past 6 months, * Known hypersensitivity or allergy to iron supplements, * Intention to become pregnant over the course of the study

What they're measuring

Serum ferritin

Timeframe: study day 1

Serum ferritin

Timeframe: study day 7

Trial details

NCT IDNCT06657677

SponsorJessica Rigutto

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-16

View on ClinicalTrials.gov More Iron Deficiency (Without Anemia) trials