CompletedNot Applicable

Effect of Cryotherapy and Laser Application on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis Cases

Egypt45 participantsStarted 2023-08-01

Plain-language summary

This study compare the effect of applying ice after single visit endodontic treatment with lasers to reduce post operative pain .

Who can participate

Age range

18 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Vital teeth display symptomatic apical periodontitis (Symptomatic apical periodontitis was determined based on the clinical symptoms of severe preoperative pain (visual analogue scale \[VAS\] \> 60) and severe percussion pain (VAS \> 60). * Teeth, with a periapical index score (PAI) of 2 or 3 indicating small changes in bone structure and slight mineral loss respectively. * Mobility less than 1 mm in either direction. * Absence of periodontal pocket around the tooth. * Symptomatic pulpitis with spontaneous pain or lingered by cold or heat. * Teeth without pus or inflammatory exudates draining through the canal. * Teeth without anatomic variations Exclusion Criteria: * • Patient with any systemic disease. * Immunocompromised patients. * Pregnant or lactating patients. * Apparently narrow roots in which apical preparation with the #40 file would be overzealous. * Retreatment cases. * Necrotic painful teeth with absence of sinus tract for drainage. * Patients on analgesics or sedative medication up to 6 hours before treatment

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

post operative pain

Timeframe: preoperative, after 24 hours, on the third , fifth, one week & two weeks after treatment

Trial details

NCT IDNCT06657664

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-01

View on ClinicalTrials.gov More Irriversible Pulpitis With Apical Peridontitis trials

Who can participate

Age range

18 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.