CompletedNot Applicable

The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery

Egypt32 participantsStarted 2023-10-08

Plain-language summary

To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients of both sexes undergoing elective open-heart surgery Exclusion Criteria: * Patients with a history of neurological disorders, severe renal or liver dysfunction, or contraindications to Dexmedetomidine as in patients with known QT prolongation, a history of other arrhythmias, symptomatic bradycardia, hypokalemia, or hypomagnesemia, and in patients receiving other drugs known to prolong the QT interval. Patients with cognitive impairment, mental and psychological illness and chronic alcoholics, drug addicts, abuse of psychotropic substances, illiterate education

What they're measuring

Postoperative cognitive function

Timeframe: Preoperative baseline, and at 1 day, 3 days, and 7 days after surgery

Trial details

NCT IDNCT06655025

SponsorSohag University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-08

View on ClinicalTrials.gov More Cardiac Surgery trials