CompletedNot Applicable

Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia

Egypt162 participantsStarted 2024-10-27

Plain-language summary

Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5). In this study, we aim to evaluate the effect of intravenous administration of albumin as a colloid preload on the maternal stroke volume (SV) and cardiac output (CO) versus crystalloid coload. We used TTE to measure the changes in SV, and CO at baseline and at subsequent time points after spinal anesthesia.

Who can participate

SexFEMALE

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Inclusion Criteria: * American Society of Anesthesiologists physical status II parturients with full term singleton pregnancies scheduled for elective cesarean delivery under spinal anesthesia. Exclusion Criteria: * Height \<150 cm, weight \<55 kg, and body mass index ≥40 kg/m2. * Women presenting in labor or having any contraindication to spinal anesthesia (patient refusal, increased intracranial pressure, coagulation disorders, or local skin infection). * Chronic or pregnancy-induced hypertension; baseline systolic blood pressure \>140 mm Hg. * Hemoglobin \<10 g/dL. * Diabetes mellitus. * Cardiovascular, cerebrovascular, or renal disease. * Polyhydramnios or fetal abnormalities.

What they're measuring

Changes in Cardiac Output

Timeframe: Immediately after delivery of baby

Trial details

NCT IDNCT06654687

SponsorSameh Fathy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-15

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