Title: The Role of Vancomycin Powder in Reducing Sternal Wound Infections Following Cardiac Surgery: A Randomized Controlled Trial Introduction: Sternal wound infections (SWIs) are significant complications in cardiac surgery, leading to serious issues like mediastinitis, prolonged hospital stays, and higher healthcare costs. This study explores the potential of topical vancomycin powder to reduce SWIs when added to the standard use of systemic antibiotics. Objectives: To assess the effectiveness of vancomycin powder in preventing SWIs post-cardiac surgery. To determine its impact on postoperative hospital stays. Study Design and Methodology: A randomized controlled trial will be conducted at Liaquat National Hospital, Karachi, with 24 patients (12 in each group). Group A will receive standard wound closure, while Group B will receive vancomycin powder applied to the sternal wound. Postoperative wound assessments will be conducted at 48 hours, 7 days, and 1 month. Ethical Considerations: Ethical approval will be obtained, and informed consent will be sought from all participants
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Incidence of sternal wound infections (SWIs) following cardiac surgery
Timeframe: he patients will be evaluated at three key time points: 48 hours post-surgery 7 days post-surgery 1 month post-surgery
Qaiser Aziz qaiserazizdr@hotmail.com, FCPS