Epidemiology, Diagnosis, Medical Care and Prognosis of Tubulointerstitial Nephritis: Results of a Multicenter Retrospective Cohort Study

Inclusion Criteria: * Adult patients who do not object to the use of their medical data and samples for this research * With a biopsy of the care on native kidney and subject to a biological collection, finding tubulointerstitial nephritis in the foreground and retained as the main cause of renal dysfunction after etiological investigation. * Signs of histological activity of the NTI objectified during the centralized rereading and defined by: * An inflammation of more than 10% of the surface of the entire cortical parenchyma (fibrous and non-fibrous) or a ti score \> or = 1 according to the Banff classification * AND/OR the presence of at least one granuloma on the biopsy Exclusion Criteria: * No access to medical records for data collection, or insufficient clinical data * Follow-up less than 3 months * Histological lesions of the tubulointerstitial sector but related to a hematological, urological, genetic etiology or the direct tubular toxicity of a drug