Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy (NCT06646172) | Clinical Trial Compass
RecruitingNot Applicable
Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy
China38 participantsStarted 2024-10-24
Plain-language summary
In light of the ongoing controversy surrounding the efficacy of bupivacaine liposomes, our study was designed to investigate, for the first time, the differential postoperative analgesic effects between bupivacaine liposomes combined with bupivacaine hydrochloride and bupivacaine hydrochloride alone in transverse thoracic muscle plane block treatment. The aim is to provide evidence-based medical guidance for drug selection in regional block local anesthesia.
Who can participate
Age range
18 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 18-90 years;
* ASA Class I \~ III;
* Patients undergoing elective median sternotomy.
Exclusion Criteria:
* Emergency surgery;
* Re-operation;
* Coagulation dysfunction;
* Preoperative left ventricular function was poor (ejection fraction \<35%);
* Systemic infection or injection site infection;
* Neuromuscular diseases;
* Mental illness;
* Dependence on psychotropic drugs;
* Allergic to bupivacaine liposomes and bupivacaine;
* Patients have participated in previous trials or have been determined by a surgeon or anesthesiologist to be unsuitable for randomization;
* Failure to obtain written informed consent from the patient or his/her representative
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.