CompletedNot Applicable

Using Probiotics to Improve Oral Hygiene During Orthodontic Treatment

Syria50 participantsStarted 2023-03-05

Plain-language summary

Fifty patients needing non-extraction-based metallic orthodontic treatment will be divided randomly into the probiotic group and the control group. In each group, they will brush their teeth regularly while receiving orthodontic treatment. Only the probiotic group will take probiotic tablets for six months. Clinical parameters will be assessed before and during orthodontic treatment and after 3 and 6 months during treatment.

Who can participate

Age range18 Years – 25 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adult healthy male and female patients aged 18-25 years.
✓. Patients eligible for full arch upper and lower fixed labial orthodontic appliance treatment and molar band.
✓. Patients with malocclusion class I, II, or III without crowding on the anterior teeth.
✓. Permanent occlusion and existence of all the upper and lower teeth (except third molars).
✓. Good oral and periodontal health:

Exclusion criteria

✕. Previous orthodontic treatment history.
✕. Patients with any systemic disorder that could influence periodontal conditions or response to treatment (such as hypertension, diabetes, or immunological disorders).
✕. Patients were on systemic drugs, i.e., antibiotics, hypertensives, analgesics, hormonal drugs, sedatives, and anti-seizure medication, within three months before the baseline examination.
✕. Patients who were allergic to ingredients of the probiotics lozenges.
✕. Those undergoing periodontal treatment within three months before the baseline examination.
✕. Smokers, pregnant or lactating women.
✕. Regular use of antibacterial mouthwash.

What they're measuring

The change in the plaque index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in the gingival index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in papillary bleeding index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in the probing depth

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

Trial details

NCT IDNCT06641960

SponsorDamascus University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-06

View on ClinicalTrials.gov More Orthodontic Appliance Complication trials

Plain-language summary

Who can participate

Age range18 Years – 25 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adult healthy male and female patients aged 18-25 years.
✓. Patients eligible for full arch upper and lower fixed labial orthodontic appliance treatment and molar band.
✓. Patients with malocclusion class I, II, or III without crowding on the anterior teeth.
✓. Permanent occlusion and existence of all the upper and lower teeth (except third molars).
✓. Good oral and periodontal health:

Exclusion criteria

✕. Previous orthodontic treatment history.
✕. Patients with any systemic disorder that could influence periodontal conditions or response to treatment (such as hypertension, diabetes, or immunological disorders).
✕. Patients were on systemic drugs, i.e., antibiotics, hypertensives, analgesics, hormonal drugs, sedatives, and anti-seizure medication, within three months before the baseline examination.
✕. Patients who were allergic to ingredients of the probiotics lozenges.
✕. Those undergoing periodontal treatment within three months before the baseline examination.
✕. Smokers, pregnant or lactating women.
✕. Regular use of antibacterial mouthwash.

What they're measuring

The change in the plaque index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in the gingival index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in papillary bleeding index

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months

The change in the probing depth

Timeframe: Time Frame: T0: immediately before applying the fixed appliance; T1: at three months; T2: at six months