Active — Not RecruitingNot Applicable

CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools

Canada500 participantsStarted 2024-10-10

Plain-language summary

Viral respiratory tract infections are very common in children. They contribute to missed time in school, work disruption for caregivers and can also cause severe illness requiring hospitalization and rarely death. In the 2022-2023, influenza, RSV and SARS-CoV-2 viruses infected a large number of children which strained the pediatric healthcare system in many jurisdictions. Unfortunately, there continues to be limited data on duration of infectiousness and transmission risk of these viruses to inform public health decisions during times when there is significant circulation of these viruses.

Who can participate

Age range1 Day

SexALL

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Inclusion criteria

✓Any individual in the same household (i.e. household contacts, defined as residing at the same address) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis
✓Any individual in the same classroom (i.e. classroom contacts) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis (i.e. case identified through the THS program)

Exclusion criteria

✕Participants will be ineligible if they are more than 5 days from symptom onset

What they're measuring

To describe the viral dynamics of influenza, RSV and SARS-CoV-2 over time among children <18 years of age.

Timeframe: 14 days

Trial details

NCT IDNCT06640387

SponsorThe Hospital for Sick Children

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-04-02

View on ClinicalTrials.gov More SARS CoV 2 Infection trials