CompletedNot Applicable

The Effect of Cosmetic Face Care Products on Facial Skin Tone and Spot Brightening

India250 participantsStarted 2024-10-22

Plain-language summary

This is a single centre, 5-cell, blinded study to evaluate changes in even skin tone, skin glow, facial pigmented spots, and the microbiome of facial skin following the use of cosmetic face care products on the whole face over a 12 week period.

Who can participate

Age range

20 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female adult participants in general good health as determined from a recent medical history. * Participants in the age group of 20-45 years (both ages inclusive). * Participants having Fitzpatrick photo-type III-V. * Participants with at least 3 spots on the cheek either of PIH post acne/age related * Participants not presenting any skin condition that may interfere with the assessment for the entire study duration. * Participants free of excessive hair, acne, cuts, abrasions, fissures, wounds, lacerations, or any other active skin conditions on the face * Participant who agrees not to use any other product/treatment/home remedy/serum on their face during the study period other than the study product. * Participants who agree to remove all jewellery on/around face (e.g., necklace, earrings, nose ring), during imaging. * Participants willing to give a voluntary written informed consent and photography release. * Participants willing to abide by and comply with the study protocol. * Participants able to read, understand and sign an appropriate informed consent form indicating her willingness to participate. * Participants willing and capable to follow the study rules and a fixed schedule. Exclusion Criteria: * Participants who are currently participating in a similar study or have participated in a similar study in the past 6 weeks. * Participants with any other signs of significant local irritation, erythema, or skin disease on skin. * Participants ha…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Visual assessment of skin colour

Timeframe: 0-12 weeks + 6 weeks regression

Instrumental assessment of skin colour

Timeframe: 0-12 weeks + 6 weeks regression

Trial details

NCT IDNCT06640244

SponsorUnilever R&D

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-11-13

View on ClinicalTrials.gov More Pigment Spots trials