CompletedNot Applicable

The Effect of Bone Marrow Stem Cells Harvested from the Iliac Crest Versus Mandibular Ramus in Alveolar Cleft Regeneration

Egypt12 participantsStarted 2021-04-15

Plain-language summary

This comparative and prospective study was conducted on 10 patients with alveolar cleft defects. Patients with alveolar cleft defects were randomly selected and randomly divided into two equal groups: Group A: received Autologous (BMMSCs) harvested from the mandibular ramus and seeded on a collagen sponge in combination with nanohydroxyapatite. Group B: received Autologous (BMMSCs) harvested from the lilac crest and seeded on a collagen sponge in combination with nanohydroxyapatite.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient aged 8-15 years, not received any surgery for alveolar cleft defect, non-syndromic unilateral alveolar cleft with or without cleft palate, good oral hygiene and good compliance with the plaque-control instructions, medically fit for major surgical oral procedure. Exclusion Criteria: * pre-existing infection at the cleft site, patients with systemic diseases may affect bone healing.

What they're measuring

The utilization of Mandibular Ramus-derived BMSCs presents a groundbreaking advancement in maxillofacial reconstruction. This approach offers numerous advantages, including reduced surgical complications

Timeframe: 6 months

Trial details

NCT IDNCT06636643

SponsorFaculty of Dental Medicine for Girls

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2021-05-20

View on ClinicalTrials.gov More Cleft Lip and Palate trials