This study aims to investigate the intervention effects of navigated repetitive transcranial magnetic stimulation (rTMS) on craving regulation in individuals with internet gaming disorder (IGD). The primary objectives include: (1) examining the impact of navigated rTMS over the dorsolateral prefrontal cortex (DLPFC) on the gaming cravings, and craving regulation capacity; and (2) exploring the potential neural mechanisms by which rTMS over the DLPFC improves craving intensity, and craving regulation ability.
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Change in craving scores in the Cue-Reactivity(CR) task
Timeframe: Approximately 10 minutes during real rTMS condition and sham rTMS
Changes in the DLPFC and craving-related brains (striatum, amygdala) activities in the ROC task following rTMS and sham rTMS
Timeframe: Approximately 14 minutes - 29 minutes after real rTMS and sham rTMS
Alterations in the functional connectivity between the DLPFC and other brain regions in the ROC task following rTMS and sham rTMS
Timeframe: Approximately 14 minutes - 29 minutes after real rTMS and sham rTMS