RecruitingNot Applicable

Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion

China200 participantsStarted 2021-11-22

Plain-language summary

This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy evaluation and prognostic prediction of the LVO patients with low NIHSS.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Aged 18 years or older
✓. Acute ischemic stroke patients of NIHSS 0-5 with 24 hours after onset
✓. Proximal intracranial artery occlusion on NCCT/CTA or MRI/MRA showing occlusion of the intracranial ICA, M1, or proximal M2 vessel
✓. Baseline ASPECTS ≥6 or infarct Core Volume of \< 70 on NCCT/DWI/CTP
✓. Pre-mRS≤1

Exclusion criteria

✕. Any sign of intracranial hemorrhage on baseline CT/MR;
✕. Seizures at stroke onset
✕. Baseline blood glucose of \<2.78 mmol or \>22.20 mmol, or platelet count \< 100,000/uL or serum creatinine levels \> 3.0 mg/dL
✕. Participation in any investigational study in the previous 30 days

What they're measuring

modified Rankin Scale at 90 days

Timeframe: 90 days

acute neurological deterioration

Timeframe: 24 hours

Trial details

NCT IDNCT06633809

SponsorSir Run Run Shaw Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-31

View on ClinicalTrials.gov More Stroke, Acute trials