A Phase II, Single-center, Single-arm Study Evaluating the Safety and Efficacy of Golidocitinib in the Management of Newly Diagnosed Peripheral T Cell Lymphoma Patients (GOLDEN Study) and Correlative Study

Inclusion Criteria: * Provision of a signed and dated, written informed consent form prior to any study specific procedures, sampling, and analyses. * Submission of the tumor block or unstained slides from an excisional or core biopsy from nodal or extra-nodal lymphoma tissue (archived or newly obtained sample) is required for retrospective central confirmation of tumor histological subtype. * Aged ≥ 18 years old. * Participants must exhibit Eastern Cooperative Oncology Group (ECOG) performance status 0-2 with no deterioration over the previous 2 weeks. * Predicted life expectancy ≥ 12 weeks. * Participants must have histologically confirmed peripheral T-cell lymphoma by MD Anderson pathology review according to the 2016 revision of the World Health Organization classification of lymphoid neoplasms53. Eligible histological subtypes are restricted to the following: * PTCL, not otherwise specified (PTCL, NOS) (the proportion of PTCL-NOS subtype will not exceed 30% of all enrolled) * Angioimmunoblastic T-cell lymphoma (AITL) * Follicular T cell lymphoma * PTCL with T follicular helper (TFH) phenotype * Participants must have measurable disease according to the 2014 Lugano classification, which is defined as lymphomatous nodes, nodal masses, or other lymphomatous lesions are measurable in two diameters (longest diameter \[LDi\] and shortest diameter perpendicular to the LDi \[SDi\]) on CT scans, and also with LDi as below: * A measurable node must have an LDi greater…