Not Yet RecruitingNot Applicable

IVUS CHIP UPP Registry

1,010 participantsStarted 2025-09

Plain-language summary

The IVUS CHIP UPP Registry is a prospective, observational, multicenter, single-arm registry. A total of 1010 patients with complex coronary lesions will be enrolled in up to 2 years, with at least 500 men and women. All patients will be treated with IVUS-guided PCI.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. The patient must be ≥18 years of age and self-identify within a US census-defined minority
✓. Patients with an indication for PCI of at least one lesion satisfying any of the following criteria:
✓. Angiographic heavy calcification
✓. Ostial lesions
✓. True bifurcation lesions involving side-branches \&gt;2.5mm
✓. Left main lesions
✓. Chronic total occlusion
✓. In-stent restenosis

Exclusion criteria

✕. ST-elevation myocardial infarction or cardiogenic shock within prior 7 days
✕. Known untreated severe valvular heart disease
✕. Contraindication on the use of IVUS (i.e. extreme vessel tortuosity)
✕. Requiring PCI in a diseased aorto-coronary bypass
✕. Known contraindication or hypersensitivity to anticoagulants
✕. Absolute contraindications or allergy that cannot be pre-medicated, to iodinated contrast or to antiplatelet drugs, including both aspirin and P2Y12 inhibitors
✕. Non-cardiac co-morbidities with a life expectancy less than 1 year
✕. A patients that is currently participating in a clinical trial that has not yet reached its primary endpoint cannot be included in this registry. A patient may only be enrolled in this registry once.

What they're measuring

Target-vessel failure (TVF)

Timeframe: 1 year after enrollment

Trial details

NCT IDNCT06625801

SponsorECRI bv

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2028-03

Contact for this trial

Chantal Bakker

31+102062828 CBakker@cardialysis.nl

View on ClinicalTrials.gov More Coronary Artery Disease trials