RecruitingNot Applicable

Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation

United States160 participantsStarted 2025-10-08

Plain-language summary

The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width condition (expansion or no change) is a determinant of buccolingual ridge width and height changes 4 months following extraction and ridge preservation.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (18-75 years) * Good general health (controlled conditions) * Controlled periodontal disease * Scheduled for single tooth extraction with bone graft placement and resorbable membrane * Tooth to be extracted must have adjacent teeth * Socket wall integrity Exclusion Criteria: * Smoking * Pregnancy * Active periodontal disease * Systemic conditions that affect healing * Lack of socket wall integrity (bone loss ≥50 %) prior to extraction, teeth with severe infection requiring pre-extraction antibiotic treatment to control infection), and contraindications for tooth extraction.

What they're measuring

Buccolingual ridge width

Timeframe: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation

Ridge height

Timeframe: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation

Trial details

NCT IDNCT06624982

SponsorMarquette University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-10-01

Contact for this trial

Vrisiis Kofina, DDS, MS

4142886521 vrisiis.kofina@marquette.edu

View on ClinicalTrials.gov More Alveolar Bone Grafting trials

Plain-language summary

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Buccolingual ridge width

Timeframe: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation

Ridge height

Timeframe: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation