Conservative Management vs. Arthroplasty in Knee Osteoarthritis (NCT06623149) | Clinical Trial Compass
By InvitationNot Applicable
Conservative Management vs. Arthroplasty in Knee Osteoarthritis
Denmark2,500 participantsStarted 2024-10-01
Plain-language summary
The goal of this observational study is to learn about the long-term effects of a non-surgical management programme in people with osteoarthritis that are eligible for a knee joint replacement surgery to treat their knee osteoarthritis (KOA). The main question it aims to answer is:
\- Does the non-surgical management programme reduce the proportion of referred patients who are treated with a knee arthroplasty without reducing the health-related quality of life over a two-year perspective?
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* A diagnosis of knee osteoarthritis.
* Referral from primary care to an orthopedic department at a hospital in The Capital Region of Denmark for treatment of knee osteoarthritis
Exclusion Criteria:
* Referral declined upon initial vetting.
* Not consenting to sharing data
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing conservative management — things like physical therapy or pain medication — against knee replacement surgery, so could you help me understand which approach you think makes more sense for where my knee osteoarthritis is right now?
2Since this study is 'enrolling by invitation only,' how would I even become eligible to be considered, and is that something you could explore on my behalf?
3One of the main things this trial is measuring is how many patients end up needing knee arthroplasty surgery anyway — what does that tell us about the real risk that conservative management might not be enough for someone with my level of knee damage?
4This trial doesn't appear to be testing a new drug or device, but rather comparing two existing care paths — does that mean the risks of participating are lower than in a typical drug trial, or are there still meaningful unknowns I should weigh?
5If I'm not invited into this trial or we decide it's not the right fit, are there standard-of-care guidelines that already compare conservative treatment versus knee replacement that we could use to guide my decision anyway?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of patients undergoing knee arthroplasty surgery
Timeframe: 2 years
2
Euroqol 5 dimensions questionnaire (EQ5D)
Timeframe: Average over 2 years (collected at month 0 (enrollment), 3, 6, 9, 12, 18 and 24)