Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Funct… (NCT06620991) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery
Egypt60 participantsStarted 2024-10-10
Plain-language summary
The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.
Who can participate
Age range21 Years – 50 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age from 21 to 50 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I-II.
Exclusion Criteria:
* Patients with a medical condition that contraindicated hypotensive anesthesia, such as peripheral vascular disease, cerebrovascular stroke, carotid artery stenosis, previous myocardial infarction, ischemic heart disease, congestive heart failure, limb ischemia, uncontrolled hypertension and raised intracranial tension
* Renal disease, liver dysfunction, pregnancy.
* Patients on hypnotic or narcotic analgesic.
* History of alcohol or drug abuse.
* History of allergic reaction to any drug used in this study.
* Bleeding diathesis.
* Previous nasal surgery.
* Patients on Non-steroidal anti-inflammatory drugs (NSAIDs).
* Patients with peripheral vascular disease.