Transplantation of Autologous Non-Cultured Extracted Hair Follicle Outer Root Sheath Cell Suspension and Mini Punch Graft for Stable Non-Segmental Vitiligo Lesions
Indonesia21 participantsStarted 2022-12-01
Plain-language summary
Vitiligo is an acquired pigmentation disorder due to loss of melanocytes characterized by depigmentation macules or patches. One type of this disease is nonsegmental vitiligo (NSV). Until now, there is no satisfactory treatment for vitiligo. Vitiligo therapies are medical therapy include topical and systemic therapy, phototherapy as well as surgery. Surgical treatment is indicated in stable vitiligo, which is not responding to medical treatment. This procedure consists of tissue grafting and cellular transplantation. Mini punch graft (MPG) is the most frequently performed tissue transplantation technique, while cellular transplantation from autologous noncultured extracted hair follicle outer root sheath cell suspension (NCEHFORSCS) containing melanocyte stem cells, is currently a promising option.
Who can participate
Age range18 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Non-Segmental Vitiligo patients
✓. Minimal 1-year duration of stability
✓. Age between 18-70 years
✓. Having at least two vitiligo lesions for NCEHFORSCS transplantation and MPG procedure
✓. Have similar size, minimum of 1 cm² and a maximum of 20 cm²
✓. The distance between the two lesions at least 1 cm
✓. Location of the lesions must have a relatively similar distribution of hair follicles
✓. Not located on the palms, soles, or penis
Exclusion criteria
✕. Pregnant
✕. Active vitiligo
✕. Mixed vitiligo
✕
What they're measuring
1
Appearance of repigmentation (AOR)
Timeframe: 4 months
2
Total number of repigmentation non-segmental vitiligo (NSV) lesions