Evaluation of the Effect of Circadian Rhythm of Adrenal Glucocorticoids After Third Molar Extraction (NCT06610383) | Clinical Trial Compass
CompletedNot Applicable
Evaluation of the Effect of Circadian Rhythm of Adrenal Glucocorticoids After Third Molar Extraction
Turkey (Türkiye)20 participantsStarted 2021-11-11
Plain-language summary
This study aimed to investigate the effects of wisdom tooth surgery performed at different times of the day on pain, swelling and trismus based on changes in the circadian rhythm in the adrenal glands in patients aged between 18-25 years who applied to the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyonkarahisar Health Sciences University with complaints of pain and swelling due to wisdom teeth.
Who can participate
Age range18 Years – 25 Years
SexALL
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Inclusion criteria
✓. Patients with bilateral wisdom teeth in the lower jaw and similar impacted positions
✓. Patients with no history of trauma to the head and neck region, no congenital deformities, no degenerative joint disease, patients between the ages of 18 and 25,
✓. Patients who have not received any treatment for the adrenal gland in the last 6 months, patients who have not used antidepressant medication in the last 6 months, patients who have no cardiovascular disease, thyroid disease, diabetes, hypertension, renal failure, isolated muscle disease, rheumatological and neurological disease, and patients who have no known psychiatric disorder,
✓. Patients with good oral hygiene,
✓. Patients who can comply with the scales in the questionnaire form,
✓. Patients who have not had surgery on their lower wisdom teeth before,
✓. Patients who have not used corticosteroids and anticonvulsant drugs,
✓. Patients who have no active caries and pulpal lesions,
Exclusion criteria
✕. Patients who had undergone surgical treatment for their wisdom teeth before the study,
✕. Patients with serious systemic diseases and those taking medication,
✕. Pregnant and breastfeeding women,
✕
What they're measuring
1
Pain Assessment
Timeframe: preoperative and postoperative days 2-7
2
Evaluation of Edema
Timeframe: preoperative and postoperative days 2-7
3
Evaluation of Trismus
Timeframe: preoperative and postoperative days 2-7
4
Evaluation of Salivary Cortisol
Timeframe: preoperative and postoperative days 2-7