Not Yet RecruitingNot Applicable

Fat Injection for Rectocele Treatment: A Novel Approach

25 participantsStarted 2024-10-20

Plain-language summary

This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.

Who can participate

Age range18 Years – 60 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients aged between 18 and 60 years. * Diagnosis of rectocele confirmed by defecography, with a rectocele size of 2 cm (mild) to 4 cm (moderate). * Presenting with symptoms of obstructive defecation syndrome, including constipation, incomplete defecation, and/or vaginal bulge. * Able to provide written informed consent to participate in the study. Exclusion Criteria: * Patients who have previously undergone surgical repair of rectocele. * Presence of thrombosed hemorrhoids. * History of sclerotherapy injection for rectocele. * Diagnosis of anal stenosis. * History of coagulopathy or current use of anticoagulant or antiplatelet medications. * Refusal or inability to provide informed consent.

What they're measuring

Reduction in Rectocele Size

Timeframe: 6 months post-procedure

Symptom Relief

Timeframe: 6 months post-procedure

Trial details

NCT IDNCT06604702

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-20

Contact for this trial

Eslam Mohamed Hagagy Mohamed, MSc

01020487095 Eslam22hego@gmail.com