CompletedNot Applicable

Gingival Crevicular Fluid of Adiponectin and Resistin As Predictable Implement in Staging and Grading System of Periodontitis

Egypt60 participantsStarted 2023-09-10

Plain-language summary

The goal of this clinical trial is to evaluate the relationship between obesity and gingival crevicular fluid resistin and adiponectin in periodontitis patients as well as assess the effect of non-surgical periodontal therapy on their levels using ELISA in obese individuals. Researchers will compare different stages of periodontitis to see if degrees of inflammation and periodontal therapy related obesity

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * obese persons with Body Mass Index (BMI) more than 40 and suffering from periodontitis Exclusion Criteria: * Patients receiving either antibiotics or non-steroidal anti- inflammatory at least 3 months prior to samples collection. * Patients subjected to previous periodontal therapy 6 months before sampling. Patients with systemic or local inflammatory conditions other than periodontal disease. * Neither lactating nor pregnant.

What they're measuring

adiponectin level in gingival crevicular fluid

Timeframe: From enrollment to the end of treatment results assessment at 12 weeks

resistin level in gingival crevicular fluid

Timeframe: From enrollment to the end of treatment results assessment at 12 weeks

Trial details

NCT IDNCT06604013

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-23

View on ClinicalTrials.gov More Periodontal Diseases trials