Skin Care Regimen for Improving Photoaging Signs on the Face (NCT06603857) | Clinical Trial Compass
Not Yet RecruitingPhase 2/3
Skin Care Regimen for Improving Photoaging Signs on the Face
United States40 participantsStarted 2024-09-27
Plain-language summary
Compare the effectiveness of laser treatment using CE Ferulic versus vehicle pre/post laser.
Who can participate
Age range
30 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult males and females aged 30-70 years (Fitzpatrick I-IV 30-65 years, Fitzpatrick V-VI 30-70 years)
* Fitzpatrick skin types I-VI
* Subjects in good general health based on investigator's judgment and medical history
* Must be willing to give and sign an informed consent form and photographic release form
* Must be willing to have examinations of face and digital photographs performed of the face
* Physician evaluator classifying the subject as mild to moderate (Score 3-6) on the modified Griffiths 10-Point Scale for the face.
* The subject must be planning to undergo fractional non-ablative laser resurfacing to the face and bilateral postauricular area and be willing to comply with study protocol and complete the entire course of the study.
* Subjects using any treatment skincare products (per investigator discretion) must discontinue use of these products four weeks before the start of participating in this clinical study and for the duration of the study.
* Male subjects with facial hair must be willing to shave prior to every visit.
* Must be willing to maintain usual sun exposure
* Subject agrees to avoid tanning or use of sunless tanner during the entire course of the study
* Negative urine pregnancy test result at the time of study entry (if applicable)
* For female subjects of childbearing potential, must be willing to use an acceptable form of birth control during the entire course of the study. All systemic birth control measures must be in …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Global Fine Lines
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
2
Overall Hyperpigmentation/ Discoloration
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
3
Skin Tone Evenness
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
4
Skin Elasticity
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
5
Skin Firmness
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
6
Skin Radiance/ Brightness
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84
7
Skin Texture Smoothness
Timeframe: Screening, Baseline, Day 28, Day 56, Day 84