RecruitingNot Applicable

Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Taiwan50 participantsStarted 2024-12-10

Plain-language summary

The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis. Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * non-traumatic cardiac arrest * admitted to ICU * GCS: motor \<=5 * severity: TIMECARD score medium-risk group Exclusion Criteria: * traumatic cardiac arrest * pregnancy * intracranial hemorrhage * coagulopathy * anti-platelet or anti-coagulation use * terminal illness * pre-arrest CPC score \>=3 * GWR \< 1.2 on CT or severe hypoxic ischemic encephalopathy * CNS infection

What they're measuring

ICP difference between different temperature

Timeframe: 12 hour, day 1, 3, 7 post-ROSC

Trial details

NCT IDNCT06601842

SponsorNational Taiwan University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08

Contact for this trial

Dean-An Ling, MD

+886-02-23123456 speckle0714@gmail.com

View on ClinicalTrials.gov More Cardiac Arrest trials