CompletedNot Applicable

Isometric and Dynamic Handgrip Training Effects on Hypertension

Pakistan60 participantsStarted 2024-08-30

Plain-language summary

Essential hypertension accounts for 13 percent of total deaths worldwide, accounting for one of the major risk factors. Hypertension (high blood pressure) is when the pressure in your blood vessels is too high (140/90 mmHg or higher). Dynamic exercises, sustained hand grip contractions elicit lower systolic blood pressure and heart rate responses. So for patients undergoing exercise therapy, low intensity isometric exercises are preferable. Significant reduction is seen in mean arterial blood pressure and systolic blood pressure in individuals conducting isometric for 8 weeks in 30%. The reduction in systolic blood pressure will be clinically significant. The main objective of this study will be to determine the effects of dynamic and isometric handgrip exercise training on cardiovascular parameters in hypertensive patients Grade 1 hypertensive patients are included as per AHA and JNC7 criteria. A sample of 100 hypertensive patients will be recruited and divided into two treatment groups; G1: dynamic exercise in hypertensive patients, and G2: isometric exercise in hypertensive patients. Outcome measure will include systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and pulse pressure. Outcome measures will be assessed at baseline and 2nd and 4th weeks posttreatment.

Who can participate

Age range

30 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Gender (both) * Age (30-55 years) * Grade 1 hypertensive patients as per AHA and JNC7 criteria Exclusion Criteria: * Patients having hypertension associated due to other diseases. * Patients having joint problems of wrist, hand fingers, ligament and tendon injuries of hand and fingers. * Patients having recent hand surgeries, fracture, history of arthritis, carpal tunnel syndrome. * Patient having history of any symptoms of chest pain. * Patients having loss of consciousness during physical activity.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

6 Minute Walk test

Timeframe: Baseline; 4nd Week; 8th Week

Blood Pressure Measurements (SBP & DBP)

Timeframe: Baseline; 4nd Week; 8th Week

Trial details

NCT IDNCT06601738

SponsorRiphah International University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-30

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