CompletedNot Applicable

Acute Kidney Injury and Recovery Mode in Pediatric Liver Transplantation

China700 participantsStarted 2024-07-01

Plain-language summary

Acute kidney injury (AKI) is a common complication after pediatric liver transplantation (PLT), and renal impairment after LT has proven to be related with increased graft failure and mortality. The recovery mode of kidney injury after PLT has not been systematically studied. Therefore, in this study the investigators aimed to systematically evaluate prognosis of AKI after PLT, combine the recovery mode of AKI with related risk factors, and establish a relationship between AKI and CKD.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Patients who received a liver transplant for the first time. * Patients who were younger than 18 years of age at the time of transplant. Exclusion Criteria: * Patients with incomplete clinical data. * Patients with less than 5 years of follow-up. * Patients who have combined multiple solid organ transplants. * Patients with preoperative renal impairment (eGFR\<60ml/min/1.73 m2 or prior renal replacement therapy).

What they're measuring

Graft survival

Timeframe: Based on the most recent follow-up before December 31, 2023. The investigators collected clinical data of patients from 2014 to 2018, and followed enrolled participants until at least 5 years after surgery

Trial details

NCT IDNCT06598228

SponsorTianjin First Central Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-09-01

View on ClinicalTrials.gov More Postoperative Acute Kidney Injury trials