Evaluating the Real World Performance of an AI Based Lung Nodule Detection Tool (NCT06597968) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Evaluating the Real World Performance of an AI Based Lung Nodule Detection Tool
United States44,900 participantsStarted 2025-06-24
Plain-language summary
chest x-rays will be analyzed by AI software for a secondary read of lung nodules. Chest x-rays will either be sent to the AI tool to be read or to radiologists to read. If the image is sent to the AI tool, the AI software will generate a report on if it detects a lung nodule or not. The image will then be sent to a radiologist to determine if there is agreement or disagreement with the AI tool.
Who can participate
Age range
18 Years – 89 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Chest X-ray images of patients aged 18 - 89 years.
* Modality: CR/DR/DX.
* PA/view
* Lung nodules measuring 6 mm -30 mm (for chest X-ray images where presence of nodules is required).
Exclusion Criteria:
* Incomplete view of the chest.
* Lateral view
* Known lung cancer at the time of Chest x-ray images.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
number of patients with actionable lung nodule as measured by CT scan
Timeframe: up to one year
2
total number of patients having chest x-ray
Timeframe: up to one year
3
number of patients with high risk lung nodule as measured by CT scan
Timeframe: up to one year
4
total number of patients referred for a CT scan
Timeframe: up to one year
5
number of lung nodule positive images
Timeframe: up to one year
6
number of lung nodule negative images
Timeframe: up to one year
Trial details
NCT IDNCT06597968
SponsorUniversity Hospitals Cleveland Medical Center