CompletedNot Applicable

Nerve Transfers for Restoration of Hand Function in Cervical Spinal Cord Injury: Effects and Influencing Factors

Netherlands19 participantsStarted 2024-10-01

Plain-language summary

The goal of this observational study is to learn about influencing factors on the clinical outcomes of nerve transfers used to restore hand function in patients with cervical spinal cord injury (CSCI). Specifically, the study focuses on the reinnervation of the posterior interosseus nerve (PIN) and the anterior interosseus nerve (AIN). The main questions it aims to answer are: 1. What is the duration after nerve transfer surgery until effect is achieved? 2. What is the influence of the participants age during surgery on the effect of a nerve transfer? 3. What is the impact of time interval from the date of spinal cord injury to the date of nerve transfer surgery? Participants are not directly involved in this study since data will be retrospectively collected from the Electronic Patients Records (EPD).

Who can participate

Age range

12 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients with cervical spinal cord injury * single or multiple nerve transfers in one or both upper limbs to reanimate the posterior interosseus nerve (PIN) or anterior interosseus nerve (AIN). * Surgery performed in Medical Spectrum Twente (MST) in Enschede. * Postoperative treatment in Roessingh, Centre for Rehabilitation (RCR) in Enschede. * Surgeries performed between February 2019 and February 2024. Exclusion Criteria: * patients with pre-existing neurological comorbidities

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Duration until result of nerve transfers

Timeframe: up to 4 weeks

Trial details

NCT IDNCT06596629

SponsorRoessingh Research and Development

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-01

View on ClinicalTrials.gov More Nerve Transfer trials