Not Yet RecruitingNot Applicable

PCA Administration in Prosthetic Joint Infection

100 participantsStarted 2026-01

Plain-language summary

Determine if dietary protocatechuic acid (PCA) will affect health biomarkers in patient undergoing revision surgery for a knee prosthetic joint infection

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 3 weeks or more after total knee arthroplasty * One or more symptoms of infection, including redness, swelling, pain, increasing range of motion loss, fever, nausea, and loss of appetite. * WBC count of aspirate \>50,000 cells per μL Exclusion Criteria: * Not willing to undergo blood draw at 3 months.

What they're measuring

Change in immunity factor CXCL9 from 0 to 3 months

Timeframe: 0 and 3 months

Change in HbA1c from 0 to 3 months

Timeframe: 0 and 3 months

Trial details

NCT IDNCT06591741

SponsorDr. Dean Reeves Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-07

Contact for this trial

Kenneth D Reeves, M.D.

9139637750 deanreevesMD@gmail.com

View on ClinicalTrials.gov More Prosthetic Joint Infection trials