RecruitingNot Applicable

Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis

Italy1,350 participantsStarted 2024-03-01

Plain-language summary

LOW-TAVR is a real-world, retrospective and prospective, multicenter Italian registry aimed at evaluating the characteristics and clinical outcomes of patients with severe low flow, low gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and, in particular: * risk factors * gender differences * comorbidities * pharmacological treatment * TAVR procedural characteristics * periprocedural and in-hospital complications * clinical outcome at 30-day, 1-year, 2-year and 5-year follow-up

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * LFLG-AS diagnosis according to current European Society of Cardiology guidelines * Age 18 years or older * Written informed consent Exclusion Criteria: * LFLG-AS pseudo-severe or non-confirmed severe aortic stenosis * LFLG-AS referred for medical treatment or undergoing surgery

What they're measuring

Composite of all-cause death and hospitalization for worsening heart failure

Timeframe: 1 year

Trial details

NCT IDNCT06589063

SponsorUniversity of Salerno

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-09-01

Contact for this trial

Gennaro Galasso, MD, PhD

3497441225 ggalasso@unisa.it

View on ClinicalTrials.gov More Low Flow, Low Gradient Aortic Stenosis trials