RecruitingNot Applicable

Molecular Pituitary Imaging Using 18F-FET PET

United Kingdom20 participantsStarted 2024-09-03

Plain-language summary

The goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tumours.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria * Participant is willing and able to give informed consent for participation in the study * Male or female, age 18 or above * Presence of pituitary adenoma suspected on the basis of clinical/biochemical and/or radiological findings * Previous 11C-Met-PET/CT Exclusion criteria * Inability to give informed consent * Pregnancy or suspected pregnancy * Inability to lie supine for 30-60 minutes * Patient body habitus above scanner dimensions * Known allergy to intravenous radiographic contrast agents

What they're measuring

Maximum Standardized Uptake Values (SUVmax) over pituitary tumour on each of 11C-methionine and 18F-fluoroethyltyrosine PET scans

Timeframe: 1 day

Trial details

NCT IDNCT06584123

SponsorUniversity of Cambridge

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-02

Contact for this trial

James MacFarlane

01223 250882 jm2267@medschl.cam.ac.uk

View on ClinicalTrials.gov More Pituitary Adenoma trials