CompletedNot Applicable

Apneic Oxygenation by Transnasal Humidified Rapid Insufflation Ventilator Exchange Obstructive Sleep Apnea Patients

China56 participantsStarted 2024-09-01

Plain-language summary

The purpose of the study is to compare effectiveness of different methods of achieving oxygenation in obstructive sleep apnea patients. The investigators intend to compare transnasal humidified rapid-insufflation ventilator exchange (THRIVE) combined with nasopharyngeal airway with THRIVE alone.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients aged between 18 and 75 years requiring general anesthesia * American society of Anesthesiologists (ASA) physical status classification system: I - III * diagnosed as OSA. Exclusion Criteria: * Patients with chronic respiratory disease, uncontrolled hypertension, ischemic heart disease, congestive heart failure, increased intracranial pressure, gastroesophageal reflux disease, * patients' arterial hemoglobin saturation \< 98% after preoxygenation, * patients were nasal obstruction * patients with previous or anticipated difficult facemask ventilation or intubation, * patients with known allergy or contraindication to propofol, remifentanil, rocuronium, or midazolam. * patients who were unable to give informed consent

What they're measuring

Following the induction of general anaesthesia and muscle relaxation, the time (minutes and seconds) to peripheral oxygen saturations (SpO2) of 95%. Comparing oxygenation with THRIVE combined with nasopharyngeal or THRIVE technique.

Timeframe: duration from apnea to eighteen (18) minutes

Trial details

NCT IDNCT06581588

SponsorBeijing Tongren Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-13

View on ClinicalTrials.gov More Obstructive Sleep Apnea Syndrome trials