Stopped: Sponsor's Decision
A Study of HS135 for the Treatment of in Obese Patients with Pulmonary Hypertension and Heart Failure with Preserved Ejection Fraction (PH-HFpEF)
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Incidence and Number of Adverse Events (AEs)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Hematology): White Blood Cell Count
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Hematology): Platelet Count
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Hematology): Red Blood Cell Count
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Hematology): Hemoglobin
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Hematology): Hematocrit
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Albumin
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Aspartate aminotransferase (AST)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Alanine aminotransferase (ALT)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Alkaline phosphatase (ALP)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Total Bilirubin
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Calcium
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Creatinine
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Glucose
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Urea
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Total Cholesterol
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): High-density Lipoprotein-cholesterol (HDL-c)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Low-density Lipoprotein-cholesterol (LDL-c)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Chloride
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Potassium
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Biochemistry): Sodium
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Blood (occult)
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Ketones
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Leukocyte Esterase
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Nitrites
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Bilirubin
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Glucose
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Urobilinogen
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Protein
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): pH
Timeframe: Up to 24 weeks
Change from Baseline in Clinical Laboratory Parameters (Urinalysis): Specific Gravity
Timeframe: Up to 24 weeks