The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Mycobacterial inhibition of host macrophages
Timeframe: Up to 10 days incubation
Mycobacterial inhibition of host peripheral blood mononuclear cells (PBMCs)
Timeframe: Up to 10 days incubation