The Effect of Different Treatment Methods on the Apical Closure and Treatment Success in Permanen… (NCT06575062) | Clinical Trial Compass
CompletedNot Applicable
The Effect of Different Treatment Methods on the Apical Closure and Treatment Success in Permanent First Molars
Turkey (Türkiye)60 participantsStarted 2023-06-05
Plain-language summary
The purpose of this thesis study is to evaluate the clinical and radiographic success of direct capping and pulpotomy applications using ProRoot MTA (mineral trioxide aggregate) in lower permanent first molars with reversible pulpitis symptoms that have not yet completed their root development. Additionally, the study aims to assess the effects of these treatments on maturogenesis, specifically root development and apical closure.
Who can participate
Age range
7 Years – 10 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Ages ranging from 7 to 10 years.
* Systemically healthy individuals.
* Have symptomatic reversible pulpitis characterized by pain that starts spontaneously and does not subside for a long time but does not include throbbing or night pain.
* Patients with permanent mandibular molars exhibiting open root tips, classified as Moorrees stages R½, R¾, Rc, or A½.
Exclusion Criteria:
* Children with systemic diseases.
* Presence of signs indicative of pulp necrosis, such as fistula or swelling in the buccal/lingual region.
* Tenderness upon palpation in the buccal/lingual region.
* Pain upon percussion.
* Presence of interradicular or periradicular radiolucency on radiographic examination.
* Evidence of internal or external root resorption.
* Widening of the periodontal space.
* Teeth with caries or molar-incisor hypomineralization (MIH) that result in excessive material loss potentially leading to restoration failure.
* Patients with inflammation and hyperemia in the root pulp.
* Permanent mandibular molar teeth with closed or nearly closed root ends, classified as Moorrees stage Ac.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Clinical success after pulpotomy or direct pulp capping treatment
Timeframe: 6 Month - 1 Year- 18 month
2
Radiographic assessment after pulpotomy or direct pulp capping treatment