The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- … (NCT06573827) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- and Postmenopausal Women
Czechia100 participantsStarted 2024-09-01
Plain-language summary
The presented project aims to characterize the microbiome of healthy peri- and postmenopausal women and its correlation with the metabolome of urine and serum.
Who can participate
Age range50 Years
SexFEMALE
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Inclusion Criteria:
* Women over 50 years old
* Consent to participate in the study
* Willingness to take urine and blood samples according to the protocol
Exclusion Criteria:
* Known congenital developmental defects of the urinary tract (congenital hydronephrosis, vesicoureteral reflux, renal agenesis, and hypoplasia, multicystic and polycystic kidneys)
* Recurrent urinary tract infections (more than 3 episodes in the last 12 months)
* Presence of any lower-urinary tract symptoms (urgency, frequency, incontinence, stranguria, urge to urinate, weak urine stream, the feeling of post-micturition residue)
* The presence of a foreign body in the urinary tract - urolithiasis, urinary catheter, ureteral stent
* Acute or chronic diseases with possible influence on lower-urinary tract function
* Medications with possible influence on lower-urinary tract function
* Rheumatoid arthritis
* Diabetes mellitus