This observational study focuses on evaluating the effect of the current health care program for Danish children and adolescents with gender incongruence, which was established in January 2016. Somatic outcome parameters include growth, bone health, body composition, metabolic parameters, hormone levels and concurrent diseases. Psychosocial parameters include the trajectory of gender incongruence development, mental health, i.e. autism spectrum disorders, behavioural problems, self-harm, suicidal ideation and psychiatric diagnoses, and social context, i.e. family demographics, education, minority stress. This study aims to: 1. Characterise the psychosocial profile of all children and adolescents referred for treatment, as well as the history of gender identity development and treatment trajectories. 2. Systematically evaluate biological parameters before and during hormonal treatment with gonadotropin-releasing hormone (GnRH) analogues and cross-sex hormones, and to establish a biobank for those in hormone treatment. The investigators hypothesise that intervention with counselling and hormonal treatment is safe and has a positive impact on psychosocial well-being of transgender youngsters. The overall aim is to provide data for improving future family counselling, clinical care, patient satisfaction, patient safety and ultimately quality-of-life.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Body Mass Index (BMI)
Timeframe: 8 years
Puberty
Timeframe: 8 years
Bone mineral content (BMD)
Timeframe: 8 years
Body fat
Timeframe: 8 years
Lean body mass
Timeframe: 8 years
Reproductive serum hormone levels
Timeframe: 8 years
Adrenal serum hormone levels
Timeframe: 8 years
Blood pressure
Timeframe: 8 years
Transabdominal ultrasound of uterus
Timeframe: 8 years
Transabdominal ultrasound of ovaries
Timeframe: 8 years
Sperm count
Timeframe: 8 years
Sperm motility
Timeframe: 8 years
Morbidity
Timeframe: 8 years
Demographic characteristics
Timeframe: 8 years
Prevalence of psychiatric disorders
Timeframe: 8 years
Prevalence of Attention Deficit Hyperactive Disorder (ADHD)
Timeframe: 8 years
Prevalence of autism spectrum disorder
Timeframe: 8 years
Global level of functioning
Timeframe: 8 years
Psychosocial Disability
Timeframe: 8 years
Suicide risk
Timeframe: 8 years
Substance abuse.
Timeframe: 8 years
Personal history of gender incongruence (GI)
Timeframe: 8 years
Cultural measures
Timeframe: 8 years
Establishment of biobank
Timeframe: 8 years.