Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric… (NCT06572371) | Clinical Trial Compass
CompletedNot Applicable
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
Egypt34 participantsStarted 2022-10-01
Plain-language summary
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
All adult patients (above 18 years old) with primary pelvi-ureteric junction obstruction indicated for active intervention as
* Symptoms such as recurrent flank pain, recurrent urinary tract infection and rarely hypertension.
* Breakthrough urinary tract infections while on prophylactic antibiotics.
* Increasing renal antero-posterior diameter, or decreasing renal parenchymal thickness by ultrasound.
* Low or decreasing differential renal function, but above 10%.
Exclusion Criteria:
* Patients having poor ipsilateral renal function \< 10%.
* Patients with previous pelvi-ureteric junction obstruction repair.
* Associated renal stones.
* Patients unfit for surgery according to American Society of Anesthesiologists classification.
* Contraindications for laparoscopy as (marked obesity, large ventral hernias, gross coagulopathy, abdominal wall sepsis, vertebral deformities…).
* Pediatric patients.
* Pregnant women.
* Vesicoureteral reflux.
* Congenital renal anomalies as (horse- shoe kidney, pelvic kidney, mal- rotated kidney ...).
* Single functioning kidney.
* Malignancy.
* Refusal of written consent.