CompletedEarly Phase 1

Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth

Egypt66 participantsStarted 2023-08-15

Plain-language summary

the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode. The secondary aim of the study is to compare their antibacterial effect against streptococcus mutans and their effect on reducing the size of the lesions.

Who can participate

Age range3 Years – 6 Years

SexALL

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Inclusion criteria

✓. healthy children
✓. age range 3-6
✓. at least 2 early carious lesions

Exclusion criteria

✕. Children presenting with special health care needs or undergoing medical treatment for chronic or acute diseases.
✕. Application of fluoride varnish less than 3 months prior to study treatment.
✕. Any metabolic disorders affecting bone turnover.
✕. Concurrent participation in another clinical trial.
✕. Patients receiving any antibiotic within 1 month prior to plaque sample collection

What they're measuring

Assessing the remineralization of early carious lesions in primary teeth

Timeframe: 3,6,9 and12 months

Trial details

NCT IDNCT06566833

SponsorAlexandria University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-15

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